중국 Wuhan Desheng Biochemical Technology Co., Ltd 회사 뉴스

종종 류미노루미네센스 원리에 대해 매우 호기심이 많은 친구들이 있습니다. 데?? 역시 전에 그것에 대해 이야기했습니다. 관심이 있다면 데?? 뉴스 페이지에서 그것에 대해 배울 수 있습니다.저는 여기서 더 자세히 설명하지 않겠습니다.류미놀의 화학 발광 원리를 이해 한 후, 당신은 그것의 발광 탐지 방법에 대해 호기심을 가질 수 있습니까?루미놀? 루미놀의 세 가지 주요 발광 탐지 방법은 발광을 가속시키기 위해 촉매를 추가하고, 간접 결정에 대한 억제자를 추가하고, 결합에 의한 간접 결정입니다. 1발광 방법을 가속화하기 위해 촉매를 추가합니다. 촉매를 첨가하는 것은 현재 일반적으로 사용되는 방법입니다. 정상적인 상황에서는 수소 과산화와 루미놀 광광 시스템의 화학 광광 반응이 매우 느립니다.하지만 촉매제를 추가한 후, 반응은 매우 빠르다. 여기 있는 누군가가 이 촉매의 존재가 전체 시스템에 영향을 미칠지 묻습니다.촉매의 종류와 양은 변하지 않습니다., 즉, 전체 반응에 비해 촉매는 참여하지 않습니다. 동시에, 이러한 촉매는 특정 농도에서 검출 될 수 있습니다.그리고 전체 검출에 대한 영향은 거의 무시할 수 있습니다. 현재 루미놀의 주요 촉매는 일부 금속 복합체와 전환 금속 이온을 포함한다. 금속 복합체에는 주로 헤모글로빈과 과산화제가 포함된다.과도기 금속 이온에는 주로 Fe3+가 포함됩니다., Fe2+, Mn2+, Cr2+, 등. 화학광광 면역 검사에서 자주 사용하는 촉매는 과산화물, 특히 파리초가 과산화물입니다.일부 화합물은 페록시다즈로 표시 된 항체로 면역 반응이 발생할 수 있습니다., 그리고 이 화합물 또는 항체를 결정하기 위해 루미놀로 화학 광광 검사를 수행 할 수 있습니다. 디고킨, B형 간염 표면 항원 등.모두 이 방법으로 검출되고 분석됩니다.. 2억제제를 추가하여 간접 결정 방법: 촉매의 탐지 가속화 외에도 연구 결과 일부 억제 물질도 발견되었습니다. 이 유기 화합물은 루미놀의 화학 발광을 억제 할 수 있습니다.페놀 하이드록실 그룹을 포함하는 감소 화합물, 반응 중에 산화 물질과 반응하고 산화 물질을 감소시킬 수 있습니다.이러한 종류의 유기물질을 간접적으로 측정하기 위해. 3과잉 결합 간접 측정 방법: 마지막으로, Desheng가 도입하는 방법은 결합 반응을 통해 간접 측정을 수행하는 것입니다.여기서 결합 반응은 화학광광 반응물을 생성하거나 소비할 수 있는 하나의 반응과 다른 화학광 반응의 결합을 의미합니다.어떤 물질을 실현할 수 있도록 하는 것입니다. 간접적인 화학 광화력 결정. 예를 들어,일부 기판은 특정 효소의 작용으로 수소 과산소를 생성하고 루미놀과 함께 화학 발광을 생성합니다.화학 광화력을 측정함으로써 측정 된 기체의 순수성은 간접적으로 알 수 있습니다. Desheng은 R & D 및 생산에 초점을 맞춘 첨단 기술 기업입니다화학광광 반응제혈액 수집 튜브 첨가물, 생물학적 버퍼 및 색상 기판.그것은 독립적인 지적 재산권과 혈액 수집 튜브 첨가물 전문 생산 연구 개발 역량을 형성했습니다.100개 이상의 국내외 제조업체에 제품을 공급하고 원자재 솔루션을 제공합니다. 화학 광화력 제품에는 루미놀과 6 종류의 아크리디늄 에스테르가 포함됩니다.

How much is RMB 40 billion? I believe that most people, like me, are a relatively abstract concept, simply a big number. Suppose you win 5 million prizes in the lottery, and you win 8,000 times. If it is used to buy in vitro diagnostic reagents, how much can you buy?   How much serum separation gel can be bought for 40 billion? Usually the price of domestic serum separation gel is tens to one or two hundred per kilogram. If we calculate at 100 yuan per kilogram, 40 billion can buy 400 million kilograms of separation gel. Separating glue is generally 25 kilograms per barrel, and the barrel is about half a meter high. These barrels of separating glue can be connected to 8 million meters, which is a thousand times the height of Mount Everest and 800 times the depth of the Mariana Trench, the deepest part of the earth.   How much can be done if these separating glues are added to the vacuum blood collection tube? Generally, coagulation tubes or anticoagulation tubes with a blood collection volume of 3-5mL add 0.8-1.2g of separation gel. We calculate by adding 1g separation gel per tube. These separation gels can be made into 400 billion blood collection tubes with a tube length of 10 cm. , Then these blood collection tubes can be connected from the earth to the moon back and forth 50 times, and can also go around the earth's equator 1,000 times, and weave a scarf for the earth.   In Vitro Diagnostic Reagents How much heparin can be bought for 40 billion? If you think the separation glue is not intuitive enough, then use 40 billion to buy heparin, the price of this is much higher. We calculate at a price of about 100 yuan per gram. The money can buy 400,000 kilograms of heparin. On average, 1300 pig small intestines can extract 1 kilogram of heparin. This heparin needs to sacrifice 520 million pigs. These pigs are 4.3 of the total population of Japan. It is 1.6 times the total population of the United States and 70% of the entire European population! My goodness, if so many pig small intestines are used to extract heparin, the remaining pork is even more unimaginable.   Of course, we can’t really spend 40 billion to buy separation gel or heparin. There are many in vitro diagnostic reagents that are more expensive than heparin, such as chemiluminescence reagent acridinium ester and enzyme preparations, antigen-antibody protein preparations, and the price is even higher than that of heparin. The milligram calculation is far more than that of gold, but usually the amount of these reagents is not much at one time, so the entire supporting products involved are also many. Desheng is a manufacturer engaged in the research and development of blood testing and virus testing related reagents, and welcomes the cooperation of in vitro diagnostic reagent companies.

카보폴 940은 겉으로 보기엔 평범한 흰색의 느슨한 분말이지만 실제로 화장품과 의약품 분야에서 매우 중요한 역할을 합니다.강한 수소성 및 독특한 산성 특성은 다기능 원료로 만듭니다.그 분자 구조의 산성 그룹 함량은 52~68%에 달하며, 이는 특정 산성을 부여하고 또한 1%의 수분분산의 pH 값을 0으로 만듭니다.카보머가 알칼리성 물질에 의해 중화되면, 그 분자 사슬은 음전하의 반발로 인해 분산되고 확장된 상태를 보이게 되므로 놀라운 팽창과 점성을 나타냅니다. 카르보폴의 많은 변종들 중카르보폴 940화이트 파우더와 융합된 폴리아크릴 폴리머로서, 카보폴 940은 매우 높은 리올로기적 변형 능력을 가지고 있을 뿐만 아니라 상상할 수 없는 점도를 만들어 낼 수 있습니다.또한 밝고 투명한 젤이나 하이드롤을 형성할 수 있습니다.이것은 화장품과 제약 산업에서 필수적인 요소가 됩니다. 카르보폴 940은 물에 녹는 두꺼워주는 물질로, 1등급 효과가 있습니다.제품들에 대한 포괄적인 보호특히 첨단 화장품 및 의약품 보조 물질에서 카보폴 940의 투명한 행렬은 제품에 독특한 질감과 시각 효과를 제공합니다. 그러나 카보폴 940으로 투명한 젤을 만드는 것은 쉽지 않습니다. 물과 결합했을 때 부풀어 오르는 과정으로 인해 물에 완전히 녹는 데 충분한 시간을 부여해야합니다.시간이 너무 짧다면, 카보머는 젤의 품질에 영향을 미치기 쉬운 집약 물질입니다. 또한 시스템의 다른 구성 요소도 고려해야 할 요소입니다.꽃수와 추출물 등카르보폴 940의 성능에 영향을 줄 수 있는 전해질을 포함합니다. 다음으로, 우리는 카르보폴 940 투명한 젤을 구성하는 과정을 자세히 살펴 보자. 먼저, 바구니에 카르보폴 940의 적절한 양을 추가, 알코올의 작은 양으로 습하게,그리고 전분산그 다음 분산 된 카보폴 940을 80 °C의 물에 담아내십시오. 섞이지 않고도 카보폴 940은 기본적으로 4-6 시간 내에 녹을 수 있습니다.물 이 쉽게 침투 하고 팽창 할 수 있게 하기 때문 이다. 카르보폴 940 용액을 준비 한 후 다른 구성 요소를 카르보폴과 혼합 할 수 있습니다. 젤의 pH 값을 조정하고 투명하고 점착성있게 만들기 위해트리에타놀라민이나 차와 같은 알칼리성 물질은 중화로 사용될 수 있습니다.그러나 트리에타놀라민의 양은 통제하기가 어렵고 과도한 사용은 시스템을 희석 할 수 있음을 유의해야합니다.중화시키기 위해 희석 된 차 (예를 들어 10% 수분 용액) 를 사용하는 것이 좋습니다.. 추가 과정 동안, 섞는 동안 시스템에서의 변화를 관찰하십시오. 시스템이 투명해지고 상태가 점성이 높아지면 pH 값을 테스트 할 수 있습니다. 후베이 신데?? 소재 회사. 웅베이성 에조 시, 게디안 개발 구역의 연합 과학 기술 도시에 위치하고 있습니다. 그것은 연구 개발, 생산,판매, 생화학 반응제 및 폴리머 물질의 기술 서비스. 생산하는 카보폴 940은 우수한 투명성과 안정적인 품질로 고객들로부터 광범위한 신뢰를 얻었습니다.수입 및 수출권을 가진 기업으로서, 신데?? 은 국내 시장에서 높은 평판을 누릴뿐만 아니라 국제 시장에서도 적극적으로 탐구하고 글로벌 고객에게 고품질 제품과 서비스를 제공합니다.

Blood collection tube additives are the core raw materials in blood collection tubes, and their quality directly determines whether the clinical test can be performed in time, the accuracy of the test results and the reliability of the diagnosis results. As a manufacturer of blood collection tube additives, Desheng has the responsibility and obligation to provide customers and patients with additives of stable quality to ensure the accuracy and timeliness of the test results. In the past, separation gel was mainly used for serum biochemical testing, that is, separation gel and blood coagulant were used in conjunction. With the development of blood collection tube technology and inspection requirements, more and more blood collection tubes have begun to use separating gel test tubes. At present, there are blood collection tubes (separation gel + potassium salt anticoagulation tube), electrolyte test tubes (separation gel + heparin salt), blood coagulation test tubes (separation gel + sodium citrate) and other varieties of blood collection tubes that use separation gel. These aspects have driven the increasing use of separating glue. But in the process of using it will always encounter various problems. A. Difficulty in adding glue: mainly because the temperature is too low. In winter, the temperature drops, the weather is cold, and the viscosity of the separating glue increases, making the process of adding glue more difficult. On the one hand, adding glue in winter is solved by heating. Separating glue generally can withstand high temperatures below 80°C without any problem. Now many equipment manufacturing companies' glue adding machines are equipped with heating function, which provides solutions for blood collection enterprises. In addition, some problems can be solved by reducing the viscosity of the separating glue, but it is not a fundamental solution. B. Flowing: After the separation glue is added, when the test tube is placed flat, the separation glue flowing distance will be too large, and some even flow to the nozzle of the tube. This is because the intermolecular chemical forces of the separating glue have not been fully recovered during the process of adding glue, and the network state has not been formed. The first solution is to increase the thixotropy of the separating glue, but it will cause difficulty in adding glue; the second is to put it upright for a few hours, and then lay it flat after the thixotropy of the separating glue recovers. C. Bubble problem: After adding glue and vacuuming, bubbles will appear in the separating glue, or bubbles will also appear after irradiation sterilization. This is because the separation glue clamps air invisible to the naked eye during the glue adding process. After being heated under vacuum or irradiation sterilization, the air in the separation glue slowly expands and becomes visible bubbles. In the process of separating glue production and adding glue, it is necessary to reduce air entrapment in the separating glue as much as possible. D. The problem that the separation gel does not turn over: Some separation gel blood collection tubes will not turn over clinically, usually because the centrifugal force is not enough, or the centrifugation time is not enough. Increasing the centrifugal force or prolonging the centrifugal time will basically solve the problem. There are also some separation glues that do not turn over due to factors such as aging, which is a quality problem of the separation glue. E. Flip the separating gel to the serum: This is caused by the too small specific gravity of the separating gel. In recent years, this situation has basically not occurred. Our company once caused this situation due to detection errors around 2010, which caused great problems to customers and the company suffered a lot. F. Detector alarm: The alarm problem of separation gel blood collection tube often occurs in clinical testing.In the past, the industry always thought that it was caused by the oil droplets or fragments of the separating glue. After years of tracking and analysis, we have found the root cause of this problem. The alarm of the instrument is usually centrifuged under the condition of incomplete blood coagulation, causing the fibrin filaments to float in the serum. When the probe is aspirated, the fibrin filaments are sucked into the probe, causing the instrument to block and alarm.

Dipotassium ethylenediaminetetraacetate is abbreviated as EDTA-2K. Its appearance is white crystalline powder. It is soluble in water and slightly soluble in alcohol. Its aqueous solution has a pH of about 5.3 and a melting point of 272 °C. Dipotassium ethylenediaminetetraacetate has a wide range of uses. It can be used to complex metal ions and separate metals. It is also used in detergents, liquid soaps, shampoos, agricultural chemical sprays, antidotes, and is commonly used in blood anticoagulants. Dipotassium ethylenediaminetetraacetate (EDTA-2K) Dipotassium ethylenediaminetetraacetate can be used for complete blood counts. Whole blood cell analysis is widely used in clinical testing. Platelet count has become an important basis for the diagnosis and treatment of clinical thrombosis and bleeding diseases, and it is also one of the important parameters for preoperative detection of surgical patients. The International Committee for Blood Standards recommends the use of dipotassium ethylenediaminetetraacetate (EDTA-K2) anticoagulant blood for complete blood counts. Studies have also explored the detection of total bilirubin (TBIL), direct bilirubin (DBIL), total protein (TP), albumin (ALB), and alanine in anticoagulated plasma and serum of dipotassium ethylenediaminetetraacetate. Differences in the results of 8 liver function indexes including aminotransferase (ALT), aspartate aminotransferase (AST), γ-glutamyltransferase (GGT), alkaline phosphatase (ALP) and so on. Methods The above eight biochemical tests were performed on EDTA-K2 anticoagulated plasma and serum on an automatic biochemical analyzer, and the results were compared and evaluated. The results showed that EDTA-K2 anticoagulated plasma compared with serum, the results of TBIL, TP, ALB, ALT, AST were not statistically significant, EDTA-K2 anticoagulated plasma ALP was significantly lower than that of serum, the difference was statistically significant, and GGT was slightly lower In serum, the difference was statistically significant, and DBIL was significantly higher than that in serum, and the difference was statistically significant. Therefore, EDTA-K2 anticoagulated plasma can be used for the detection of TBIL, TP, ALB, ALT, and AST. It is not suitable for the detection of DBIL and ALP. For the GGT test results, the reference range of EDTA-K2 plasma should be formulated or multiplied by the correction factor. Application of dipotassium ethylenediaminetetraacetate (EDTA-2K): 1. Additives for vacuum blood collection tubes: The additive of vacuum blood collection tubes is an aqueous solution of dipotassium ethylenediaminetetraacetate (EDTA-2K), and 4mg of dipotassium ethylenediaminetetraacetate (EDTA-2K) is required for anticoagulation of 2ml of blood. Because the concentration is small, in order not to dilute the blood, 20μl of an aqueous solution containing 200g/L of ethylenediaminetetraacetate (EDTA-2K) 200g/L is generally pre-installed in each blood collection tube. The validity period of the blood collection tube is two years. When the operating environment changes slightly, such as temperature changes, water can easily evaporate to the pipe wall (especially the water in the plastic PET pipe solvent can penetrate the pipe wall and leak out), causing the EDTA-2K in the pipe to crystallize and crystallize quickly When collecting blood, the latter dipotassium ethylenediaminetetraacetic acid blood collection tube is required to be turned upside down at least 8 times in order to fully dissolve and mix the crystallized EDTA-2K in the blood. If the action is too large, the red blood cells will be destroyed and hemolyzed. Gathered and adhered and broken. 2. Prepare toilet deodorant. In parts by mass, it includes the following substances: 5-10 parts of acid salt, appropriate amount of ammonia, 50-70 parts of alcohol, 5-10 parts of urotropine, appropriate amount of dipotassium edetate, appropriate amount of isobutanolamine, water 60 to 80 copies. The deodorant can not only deodorize but also prevent scale, and the method of use is simple, the dosage is small, and the duration is long, and it has no corrosive effect on the toilet. The production method is simple, the raw material cost is low, and it is non-toxic, harmless and non-polluting. 3. Used as a complexing agent in liquid phase analysis. If the invention provides a tetrabutylammonium hydrogen sulfate buffer salt system for liquid chromatography detection, the solvent is water, and the solute includes tetrabutylammonium hydrogen sulfate and a buffer ion pair. The buffer ion pair is composed of potassium dihydrogen phosphate and phosphoric acid The solute also includes a complexing agent, and the complexing agent is preferably dipotassium ethylenediaminetetraacetate. The tetrabutylammonium hydrogen sulfate buffer salt system provided above is stable within 24 hours without turbidity. Taking the analysis of related substances of moxifloxacin hydrochloride as an example, it can be seen that the tetrabutylammonium hydrogen sulfate buffer salt system stored at room temperature for 24 hours The chromatographic behavior of moxifloxacin, N-methyl impurity, impurity A, impurity B, impurity C, impurity D, and impurity E on the reversed-phase chromatography column is basically the same as that of the newly configured tetrabutylammonium hydrogen sulfate buffer salt system. 4. Prepare metal polishing agent. The polishing agent is based on dipotassium ethylenediaminetetraacetate (EDTA-2K), trisodium phosphate, dibutyl phthalate, sodium silicate, inorganic acid, dicarboxylic acid compound, tetrapolyricinoleate, biological Buffer, stabilizer, water-soluble surfactant, water as raw materials, and through a scientific content ratio, the polishing agent prepared from this can effectively remove impurities on the metal surface. It is not only convenient to operate, but also has a good polishing effect. Improve the production efficiency, and ensure the cleanliness and gloss of the metal surface, and improve the quality of the metal. Desheng has been committed to the research and development of blood collection tube additives. It has 15 years of production experience and can provide customers with lithium heparin, sodium heparin, dipotassium EDTA and tripotassium EDTA. If you need it, please call for details.

전체 이름HEPES 버퍼4-하이드록시에틸피페라진 에탄수플론산, CAS 7365-45-9, HEPES는 종종 생물학적 버퍼로 사용됩니다. pH 버퍼 범위: 6.8-8.2, 헤페스 버퍼의 주요 성분은 하이드록시 에틸 피페라진 에틸 황산입니다.pH 범위 7에서 좋은 펌퍼 능력을 가지고 있습니다..2-7.4주로 생화학 진단 키트, DNA/RNA 추출 키트 및 PCR 진단 키트에서 사용됩니다. 다양한 생화학적 반응에 사용됩니다. 1. HEPES버퍼다양한 종류의 유기체의 세포 배양 매체, 세포-세포 접착, 단기 세포 집적 및 배양, 조직과 세포를 청소하는 버퍼 반응제로 자주 사용됩니다. 2단백질 연구에서, PIPES는 종종 카티온 교환 염색체에서 결합 버퍼의 구성 요소 및 전액으로 사용됩니다. 3DNA 연구에서, PIPES는 칼슘 포스파트 및 DNA 침착물 형성 시스템, 그리고 AFM 및 전극화 실험의 버퍼로 사용된다. 4또한, HEPES는 DNA와 제한 효소 사이의 반응에 약간의 간섭을 가지고 있으며, 로우리의 방법은 단백질 함량을 결정하기에 적합하지 않습니다. 5HEPES 버퍼는 종종 유기체와 매우 변동성, pH에 민감한 단백질과 효소의 연구와 생화학적 진단 키트에서 사용됩니다.DNA/RNA 추출 키트 및 PCR 진단 키트. 6. 반응 버퍼, 전융합 버퍼 및 융합 버퍼 RNA 핵 구성 요소를 분리하고 분석하기 위해; RNA 및 T4RNA에 사용됩니다.분자생물학 등급은 RNA의 3'끝을 T4 RNA 리가즈로 표시하는 데 사용됩니다., 핵 RNA의 반응 버퍼, 프리 하이브리디제이션 버퍼 및 하이브리디제이션 버퍼의 구성 요소를 분리하고 분석합니다. HEPES 분말 HEPES 관련 문제 1대부분의 세포에 필요한 pH는 7.2-7.4, 그러나 세포 배양에 적합한 pH는 배양되는 세포의 종류에 따라 다릅니다. 섬유성 세포는 더 높은 pH (7.4-7.7) 를 선호하지만 변형 된 세포 라인의 통과는 산성을 필요로합니다. pH (7.0-7.4) 대부분의 배양액은 나트륨 바이카보네트 (NaHCO3) 및 CO2 시스템으로 완충되기 때문에가스 단계의 CO2 농도는 배양액의 나트륨 바이카보네트 농도와 균형을 이루어야 합니다.가스 단계 또는 큐베이터 공기에서의 CO2 농도가 5%로 설정되면, 배양 용액에 첨가된 NaHCO3의 양은 1.97g/L입니다.농산물 용액에 첨가된 NaHCO3의 양은 3입니다..95g/L. 세포 배양 병의 뚜?? 은 가스 교환을 보장하기 위해 너무 단단하게 skrued 되지 않아야 합니다. 2HCO3 및 CO2 버퍼 쌍을 사용하는 배양 용액의 pH 값은 불안정하며 일정 기간 동안 저장된 후 알칼리 성향이 있습니다.만약 배양액의 pH가 너무 빨리 변하면, HEPES 버퍼는 10~25mM의 최종 농도로 배양액에 첨가될 수 있습니다. 3. HEPES는 암포테릭 버퍼로, 주로 산화성 인산화, 불균형 환경에서 단백질 합성, 광합성 인산화, CO2 고정 등 생물학적 연구에 사용됩니다.HEPES는 금속 이온아제의 기질에 영향을 미치지 않으며 전자 현미경 (TEM) 에서 전송에 적합합니다.; 세포 배양 매체에서 장점은 열린 배양 또는 세포 관찰 중에 비교적 일정한 pH 값을 유지할 수 있다는 것입니다.또는 고 농도의 CO2 배양 환경의 제한을 완화하기 위해 바이카보네이트 버퍼 (10-15mM) 를 추가합니다.용해된 이산화탄소와 바이카보네이트도 좋은 세포 성장에 매우 중요합니다.

전염병의 영향으로 인해 어떤 것들이 떨어지고 어떤 것들은 필연적으로 높아질 것입니다.카보메르. 교차 결합 된 아크릴 폴리머로서, 카보머는 두꺼워지는 성능과 강한 서스펜싱 능력을 가지고 있습니다. 손 세제제에서 사용되는 것 외에도 피부 관리 로션에도 널리 사용됩니다.크림, 투명 젤, 헤어 스타일 젤은 배터리에도 적용될 수 있습니다. 카보머의 주요 기능은: 1두께가 커지면 많은 점성과 유동성을 얻을 수 있습니다.2- 서스펜션: 용해되지 않는 구성 요소를 시스템에서 영구적으로 서스펜션으로 만듭니다.3에뮬레이션은 기름/물 단계에서 에뮬레이션 및 안정화를 수행합니다. 카보메르 두꺼움 메커니즘: a. 소금 두꺼움, 가장 일반적인 방법 은 산성 樹脂 을 적절 한 소금 으로 변화 시키기 로, 이렇게 卷曲 된 樹脂 분자 들 이 열려 두꺼움 을 유발 한다. 물 과 다른 극성 용매 들 에서,사용 NaOH, KOH, NH40H 이러한 중화로 소금을 쉽게 생성 할 수 있습니다. 급성 약성 또는 비 급성 용매에서 중화에 유기 아민을 사용해야합니다. 樹脂이 발효제로 사용되는 경우,기름/물 에뮬레이터의 최상의 안정성을 달성하기 위해, 수분 용해성 비 유기 염분과 기름 용해성 유기 아민으로 樹脂을 두 번 중화해야합니다. 따라서 제품은 물과 기름에 용해됩니다.소금 은 기름 상태 와 물 상태 사이 를 연결 하는 역할을 합니다. b. 가벼운 결합 두꺼움, 합성에 하이드록실 분자를 추가하여, 카복실 분자로서의 합소는 하나 이상의 하이드록실 그룹과 결합하여 두꺼워질 수소 결합을 형성할 수 있습니다.이 방법은 시간이 걸립니다.이 물질의 PH 값은 약간 산성입니다.그리고 분산은 70°C (하지만 초과해서는 안 됩니다) 로 가속화 할 수 있습니다.일반적으로 사용되는 폴리하이드록시 및 폴리에토크시 반응 물질: 비 이온적 표면 활성 물질, 용매, 폴리올, 글리콜-실란 코폴리머, 폴리 에틸렌 산화물, 완전히 수분 된 폴리 비닐 알코올 등. 사용: 카보머는 두꺼워지기, 젤링, 접착성, 에뮬레이션, 서스펜싱 및 필름 형성 특성을 가지고 있습니다. 두꺼워지기 및 에뮬레이터로서의약품 산업에서 다음과 같은 응용 분야가 있습니다.: 1느린 분비 물질로 만들어진 제어 분비 약물, 아스코르브산, 아스피린, 리?? 탄산, 아트로핀 황산, 프로카인 수소화물, 엽록산, 퀴닌 황산,테오필린 등. 2외부 의약품 의 조립에 적용, 연약, 수포토리, 크림, 젤, 에뮬션 등을 만들기 위해 운반 매트릭스. 3이 제품의 젤, 접착제 및 필름 형성 특성을 활용하여, 바이오 접착제,그것은 조직 점막에 오랫동안 남아 있고 약물의 생체 접착력을 향상시킵니다.눈, 코, 장, 질 및 직관 점막을 포함한 점막을 대상으로하는 사용. 4이 제품의 서스펜싱 능력을 활용하여 불분해 성분을 효과적으로 서스펜싱하여 균일한 분산 시스템을 형성 할 수 있습니다. 이는 안전하고 효과적인 구강 서스펜션에 사용됩니다.,냄새를 피하고 안정성을 유지하며 생체 사용성을 향상시킵니다. 생산 능력을 높이기 위해서데??새로운 장비를 적극적으로 적용하고 생산 인력을 늘립니다. 생산 능력을 보장하면서 제품 품질에도주의를 기울여야합니다.높은 수요가있는 카보머 시리즈 제품은 카보머 940 및 카보머 980입니다.데손은 고품질의 카보머 시리즈 원료를 제공할 수 있습니다.

Tris base is named tris(hydroxymethyl)aminomethane; tromethamine; tromethamine; 2-amino-2-(hydroxymethyl)-1,3-propanediol. It is a white crystal or powder. Soluble in ethanol and water, slightly soluble in ethyl acetate and benzene, insoluble in carbon tetrachloride, corrosive to copper and aluminum, and irritating chemicals.   Tris is a weak base, and its pKa is 8.1 at 25°C; according to the buffer theory, the effective buffer range of Tris buffer is between pH 7.0 and 9.2. The pH of the aqueous solution of Tris base is about 10.5. Generally, hydrochloric acid is added to adjust the pH to the desired value to obtain a buffer of the pH value. But at the same time, attention should be paid to the influence of temperature on the pKa of Tris.   Tris is often used as a biological buffer, and is often formulated with pH values ​​of 6.8, 7.4, 8.0, and 8.8. Its pH value varies greatly with temperature. Generally speaking, for every degree of temperature increase, the PH value drops by 0.03. tris structure 1M Tris-HCl 6.8 and 1.5M Tris-HCl 8.8 are the most commonly used reagents for SDS-PAGE. And TAE, TBE, etc. prepared by Tris are the most commonly used reagents for DNA electrophoresis, and TE (pH 8.0) is mainly used to dissolve DNA. (TE is the collective name of Tris and EDTA.)   Tris buffer is not only widely used as a solvent for nucleic acids and proteins, but also has many important uses. Tris is used for protein crystal growth under different pH conditions. The low ionic strength of Tris buffer can be used for the formation of the intermediate fiber of C. elegans nuclear lamin (lamin). Tris is also one of the main components of protein running buffer. In addition, Tris is also an intermediate for the preparation of surfactants, vulcanization accelerators and some drugs. Tris is also used as a titration standard.   The Tris buffer developed and produced by Desheng is used for the preparation of buffers in biochemistry and molecular biology experiments; the preparation of pharmaceutical intermediates and the preparation of kits.

Due to a sudden new coronary pneumonia in early 2020, Virus Transport Media appeared in the public eye. But what exactly does it do, I think most people still don't know. Let's first talk about the role of inactivated Virus Transport Media. What is inactivation? Inactivation refers to the use of physical or chemical means to kill viruses, bacteria, etc., but does not damage the useful antigens in their bodies.   Inactivated virus: The high-level structure of the virus protein is destroyed, and the protein no longer has physiological activity, so it loses the ability to infect, cause disease and reproduce, but the conventional inactivation does not affect the primary structure of the virus protein, which means the sequence of the virus protein no change.     Inactivated Virus Transport Media: It is a colorless and transparent liquid, suitable for various types of viruses, new coronaviruses, various influenza, avian flu, hand, foot and mouth urticaria and other viruses. A high concentration of guanidine salt is used to achieve rapid inactivation and preservation of respiratory pathogens, so that the sample loses infectivity. The inactivated samples can be used with the corresponding new coronavirus RNA extraction kit, M32/M96 nucleic acid extractor, etc. to quickly extract viral nucleic acid, and the new coronavirus PCR detection kit can be used to achieve rapid detection without specific sensitivity. influences. Applicable kit methods: fluorescent PCR method, combined probe anchoring polymerization sequencing method, constant temperature amplification chip method, magnetic particle chemiluminescence method, colloidal gold method.   It has the following advantages: 1. Efficiently inactivate viruses to avoid cross-infection caused by centralized sampling 2. Inactivate the virus, reduce the difficulty of storage and transportation 3. The sample loses its infectivity and protects the testing personnel 4. Widely used in PCR laboratory   The product developed and produced by Desheng is suitable for the collection, preservation and transportation of common virus samples such as new coronavirus, influenza virus, hand, foot and mouth virus. Pharyngeal swabs, nasal swabs or tissue samples of specific parts can be collected, and the stored samples can be used for subsequent clinical experiments such as nucleic acid extraction or purification.

Hand-washing sanitizing gel is a daily chemical product that is often used in daily life. Because of the new crown epidemic, it has made it widely welcomed by the public. Carbomer 980, a very important raw material in the sanitizing gel, has also become more and more biochemical. Favored by reagent manufacturers. Carbomer is used in hand sanitizing gel. The main reason is its thickening, viscosity and permeability. Compared with hand sanitizer, most people prefer gel products. Carbomer can be used to change the solution. It is gel-like, which is more durable and easier to use than liquids. The concentration of carbomer is basically in the range of 0.2%-0.5%. Carbomer can make the liquid system have a special yield value and rheology. Only a very low concentration can make some insoluble additives (particles, oil droplets) Etc.) Achieve permanent suspension. Carbomer 980 powder It is precisely because of the strong levitation ability of carbomer that carbomer is widely used. In addition, carbomer can achieve a good transparency effect when used in hand washing and disinfection gel. After being neutralized and ionized by the carboxyl group, due to the mutual repulsion of negative charges, the molecular chain is dispersed and stretched, showing a greatly expanded state. It is sticky, and these characteristics undoubtedly make Carbomer one of the important raw materials for hand-washing disinfection. The most notable feature of the use of hand-washing disinfection gel is that it avoids repeated washing, does not need to be washed with water, and can effectively inhibit and remove bacteria from the hands. Especially in summer, the growth rate of bacteria increases, especially intestinal pathogens, pyogenic cocci, yeasts and other pathogens. The main bactericidal component of the hand-washing disinfection gel is ethanol. If it has antibacterial effect, there will be other antibacterial agents, and some use guanidine substances to inhibit bacteria. The content of antibacterial agents is generally a few tenths of a percent, up to 23%, and the national standard also has clear requirements for the content of various antibacterial agents. With the spread of the new crown epidemic at home and abroad, the supply of disinfection products is in short supply in a short period of time. Especially the disposable hand sanitizer used to sterilize hands when going out has been snatched wildly. Carbomer 980 is used as the free hand sanitizer. As one of the ingredients, many manufacturers have raised their prices. Some manufacturers cannot supply normally because of too many orders. However, as one of the newly developed manufacturers of carbomer products, Desheng can not only guarantee the normal supply of products, but also maintain the prices. Does not rise, is a true conscientious producer.

Carbomer is a copolymer of polyalkyl sucrose or polyalkyl pentaerythritol and acrylic acid cross-linked polymer. It can form a high-viscosity gel at a very low concentration (usually 0.2-1.0%) and is widely used Daily chemical, pharmaceutical and other industries. But it has a lot of models, even with similar names, can these different models be replaced with each other? The first thing you need to understand is the meaning of different models of carbomer, mainly based on the different materials used in polymerization and the degree of polymerization, so there are a variety of different specifications and models of carbomer. Commonly used in the market are carbomer 980, carbomer 940, carbomer U20, etc., and their thickening performance, emulsification performance, viscosity, shear resistance, etc. are different, so most cases cannot be replaced by each other of. Some characteristics of different carbomers are listed below: Carbomer Clear Gel Carbomer 940: It is characterized by good thickening performance, extremely short rheology, high viscosity, medium clarity, low ion resistance and high shear resistance, suitable for creams, lotions and gels. Carbomer 941: It is characterized by stable emulsification system, low viscosity, long rheology, high-definition clarity, medium ion resistance and low shear resistance. Even in ionic solutions, stable emulsions or high Transparent gel. Carbomer 980: The viscosity is higher than 940, the ion resistance is better than 940, the transparency is equivalent, and it is nourishing than 940 when used in skin care products. Carbomer U20: excellent dispersibility, high thickening performance, long rheology, good transparency, good suspending ability, stable emulsification system, and no stickiness. It can be used in creams or lotions instead of traditional carbomer 934 , Instead of Carbomer 940 or 980 for transparent gel. Judging from the characteristics of the respective models, different carbomers are not completely irreplaceable, but generally speaking, the carbomer model used in a product is fixed, but for newly developed products, it is still necessary to test multiple models of carbomer. Therefore, it chooses the best performance, and with the update of technology, the development of better performance carbomers will come out, which will replace some traditional carbomers. Desheng Technology has many years of R&D and production experience in Carbomer and other acrylate polymer materials manufacturers, and welcomes users to communicate!

Carbomer, also known as carbomer, is a polymer formed by chemical cross-linking of acrylic acid or acrylate and allyl ether, including polyacrylic acid (homopolymer) and long-chain alkanol acrylates Polymer (copolymer). Its molecular structure contains 52-68% acid groups, so it has a certain acidity, has hydrophilic properties, and can be dissolved in water, ethanol and glycerin. Carbomer has the functions of thickening, suspending, stabilizing the system, regulating the release of water and active substances, and has simple process and good stability. Therefore, it is a rheological modification widely used in personal care products, pharmaceuticals and other fields. Thickener. There are two main thickening mechanisms of carbomer, including neutralization thickening and hydrogen bond thickening. 1. Neutralization and thickening Because it contains a certain acid group, it needs to be alkaline neutralized during the application process. After being neutralized by alkali, the carboxyl group of the carbomer is ionized. Due to the mutual repulsion of negative charges, the curled molecular chain stretches into a greatly expanded state, which increases the original volume to about 1000 times. To the effect of thickening. Commonly used neutralizers are sodium hydroxide, potassium hydroxide, potassium bicarbonate, and triethanolamine (the pH is adjusted to about 7 to get a crystal clear gel), which is why carbomer is sensitive to ions. 2. Hydrogen bond thickening Carbomer molecules, as carboxyl donors, can combine with one or more hydroxyl groups to form hydrogen bonds and thicken. This reaction mechanism takes time. Commonly used hydroxyl donors are non-ionic surfactants, polyols and so on. In addition, the following points need to be paid attention to when using carbomer. Precautions: 1. All carbomer polymers have the ability of shear thinning, and the longer the shear time, the slower the viscosity recovery, and even the permanent loss of viscosity; 2. Carbopol polymer has poor tolerance to ions, and Carbopol 1342, which is in the transitional stage, is relatively high; 3. Ultraviolet radiation will cause loss of the viscosity of carbomer, and this loss is irreversible.