중국 Wuhan Desheng Biochemical Technology Co., Ltd 회사 뉴스

How much is RMB 40 billion? I believe that most people, like me, are a relatively abstract concept, simply a big number. Suppose you win 5 million prizes in the lottery, and you win 8,000 times. If it is used to buy in vitro diagnostic reagents, how much can you buy?   How much serum separation gel can be bought for 40 billion? Usually the price of domestic serum separation gel is tens to one or two hundred per kilogram. If we calculate at 100 yuan per kilogram, 40 billion can buy 400 million kilograms of separation gel. Separating glue is generally 25 kilograms per barrel, and the barrel is about half a meter high. These barrels of separating glue can be connected to 8 million meters, which is a thousand times the height of Mount Everest and 800 times the depth of the Mariana Trench, the deepest part of the earth.   How much can be done if these separating glues are added to the vacuum blood collection tube? Generally, coagulation tubes or anticoagulation tubes with a blood collection volume of 3-5mL add 0.8-1.2g of separation gel. We calculate by adding 1g separation gel per tube. These separation gels can be made into 400 billion blood collection tubes with a tube length of 10 cm. , Then these blood collection tubes can be connected from the earth to the moon back and forth 50 times, and can also go around the earth's equator 1,000 times, and weave a scarf for the earth.   In Vitro Diagnostic Reagents How much heparin can be bought for 40 billion? If you think the separation glue is not intuitive enough, then use 40 billion to buy heparin, the price of this is much higher. We calculate at a price of about 100 yuan per gram. The money can buy 400,000 kilograms of heparin. On average, 1300 pig small intestines can extract 1 kilogram of heparin. This heparin needs to sacrifice 520 million pigs. These pigs are 4.3 of the total population of Japan. It is 1.6 times the total population of the United States and 70% of the entire European population! My goodness, if so many pig small intestines are used to extract heparin, the remaining pork is even more unimaginable.   Of course, we can’t really spend 40 billion to buy separation gel or heparin. There are many in vitro diagnostic reagents that are more expensive than heparin, such as chemiluminescence reagent acridinium ester and enzyme preparations, antigen-antibody protein preparations, and the price is even higher than that of heparin. The milligram calculation is far more than that of gold, but usually the amount of these reagents is not much at one time, so the entire supporting products involved are also many. Desheng is a manufacturer engaged in the research and development of blood testing and virus testing related reagents, and welcomes the cooperation of in vitro diagnostic reagent companies.

카보머는 강한 흡습성과 하얀 루스 파우더입니다. 그것의 분자구조는 52-68% 산성기를 포함하고 따라서 그것이 어떤 신맛을 가지고 있습니다. 1% 수성 분산액의 pH 0입니다. 겔은 알칼리성 물질에 의해 중립화될 수 있습니다. 카르복시 기가 카보머 중화에 의해 이온화된 후, 분자 사슬은 큰 확장과 점착성의 주를 보여주는 음전하의 상호 반발로 인해 전파되고 확장됩니다. 하이드로겔 시스템의 효과적 후막화 범위는 PH5-10 내에 포함됩니다.     카보폴 940 겔 카보폴 940은 백색 파우더 가교결합 폴리아크릴 산 폴리머입니다. 그것은 극단적으로 효율적 유변학적 물성이며, 그것이 고점성도를 극단적으로 생산하고 밝은, 투명 젤 또는 하이드로겔과 크림을 형성할 수 있습니다. 카보폴 940은 또한 효과적 수용성 농축기입니다. 그것은 우수한 침전 방지제, 안정기와 유화제로서 사용될 수 있습니다. 카보폴 940은 우수한 화장품과 약제학적 부형제를 위한 투명 매트릭스로서 사용될 수 있습니다. 화장용 겔에서, 물은 흡수되거나 오랫동안 균질이 되어야 합니다.   카보머 940과 물의 조합이 팽창 공정을 가지고 있기 때문에, 시간은 소실되고 덩어리로 만들기에 너무 짧습니다. 둘째로, 우리는 시스템의 다른 부품이 전해액을 포함하는지를 확인할 필요가 있습니다. 많은 자연적인 플랜트 부품은 근본적으로 전해액을 가지고 있고 꽃물과 같이 뽑아내고 추출물과 기타를 설치합니다. 거기가 전해액이 있을 때, 카보폴 940은 사용되어야 합니다.   카보폴 940 구성 투명 젤 과정 : 카보폴 940의 특수 구조물 때문에, 그것은 물이 쉽게 확대되게 하고 따라서 물에 녹기 위해 그것을 위해 시간을 곁에 설정하는 것은 필요합니다, 그렇지 않았다면 생산된 겔이 가담하기 쉽습니다.   1. 처음으로, 비례하는 카보폴 940을 비이커에 부가하고 젖고 프리 작은 술로 그것을 전파하고, 그리고 나서 80이지 Ｃ 물에서 혼냅니다. 4-6시간 동안 휘젓지 않을지라도, 그것은 근본적으로 해산됩니다.   2. 카보머 솔루션을 준비 뒤에, 다른 성분은 카보머 솔루션과 혼합되었고, pH 6-7에 차로 중화했습니다. 트리에타놀아민의 양을 제어하는 것은 쉬운게 아니기 때문에, 그것이 약간 너무 심하면 시스템은 희석되고 따라서 그것이 10% 수용액으로의 차를 희석하고, 점적기로 그것을 추가하고, 추가되는 동안 그것을 휘젓는다고 추천받습니다. 시스템이 점점 더 투명하고 주가 점점 더 두껍다는 것을 당신이 알아챌 때, pH 값을 시험하세요.   후베이 엑스인데성 물질 Co., Ltd．는 공동 과학과 기술 도시, 게디안 개발 지대, 에즈호우 시, 후베이 성에 위치합니다. 그것은 연구, 개발, 생산, 생화학 시약과 폴리머 재료을 판매와 기술 서비스, 상품의 입출과 더불어, 기술에서 종사된 회사고 요원들 (법에 따라 승인에 따른 프로젝트) 입니다, 첨단 기업으로서, 카보폴 940의 투명성이 고객들을 위한 엄격한 요구사항에 도달했고 제품 품질이 깊게 고객들에 의해 믿어집니다.

Blood collection tube additives are the core raw materials in blood collection tubes, and their quality directly determines whether the clinical test can be performed in time, the accuracy of the test results and the reliability of the diagnosis results. As a manufacturer of blood collection tube additives, Desheng has the responsibility and obligation to provide customers and patients with additives of stable quality to ensure the accuracy and timeliness of the test results.   In the past, separation gel was mainly used for serum biochemical testing, that is, separation gel and blood coagulant were used in conjunction. With the development of blood collection tube technology and inspection requirements, more and more blood collection tubes have begun to use separating gel test tubes. At present, there are blood collection tubes (separation gel + potassium salt anticoagulation tube), electrolyte test tubes (separation gel + heparin salt), blood coagulation test tubes (separation gel + sodium citrate) and other varieties of blood collection tubes that use separation gel. These aspects have driven the increasing use of separating glue. But in the process of using it will always encounter various problems.     Serum separation gel A. Difficulty in adding glue: mainly because the temperature is too low. In winter, the temperature drops, the weather is cold, and the viscosity of the separating glue increases, making the process of adding glue more difficult. On the one hand, adding glue in winter is solved by heating. Separating glue generally can withstand high temperatures below 80°C without any problem. Now many equipment manufacturing companies' glue adding machines are equipped with heating function, which provides solutions for blood collection enterprises. In addition, some problems can be solved by reducing the viscosity of the separating glue, but it is not a fundamental solution.   B. Flowing: After the separation glue is added, when the test tube is placed flat, the separation glue flowing distance will be too large, and some even flow to the nozzle of the tube. This is because the intermolecular chemical forces of the separating glue have not been fully recovered during the process of adding glue, and the network state has not been formed. The first solution is to increase the thixotropy of the separating glue, but it will cause difficulty in adding glue; the second is to put it upright for a few hours, and then lay it flat after the thixotropy of the separating glue recovers.   C. Bubble problem: After adding glue and vacuuming, bubbles will appear in the separating glue, or bubbles will also appear after irradiation sterilization. This is because the separation glue clamps air invisible to the naked eye during the glue adding process. After being heated under vacuum or irradiation sterilization, the air in the separation glue slowly expands and becomes visible bubbles. In the process of separating glue production and adding glue, it is necessary to reduce air entrapment in the separating glue as much as possible.   D. The problem that the separation gel does not turn over: Some separation gel blood collection tubes will not turn over clinically, usually because the centrifugal force is not enough, or the centrifugation time is not enough. Increasing the centrifugal force or prolonging the centrifugal time will basically solve the problem. There are also some separation glues that do not turn over due to factors such as aging, which is a quality problem of the separation glue.   E. Flip the separating gel to the serum: This is caused by the too small specific gravity of the separating gel. In recent years, this situation has basically not occurred. Our company once caused this situation due to detection errors around 2010, which caused great problems to customers and the company suffered a lot.   F. Detector alarm: The alarm problem of separation gel blood collection tube often occurs in clinical testing. In the past, the industry always thought that it was caused by the oil droplets or fragments of the separating glue. After years of tracking and analysis, we have found the root cause of this problem. The alarm of the instrument is usually centrifuged under the condition of incomplete blood coagulation, causing the fibrin filaments to float in the serum. When the probe is aspirated, the fibrin filaments are sucked into the probe, causing the instrument to block and alarm.

Dipotassium ethylenediaminetetraacetate is abbreviated as EDTA-2K. Its appearance is white crystalline powder. It is soluble in water and slightly soluble in alcohol. Its aqueous solution has a pH of about 5.3 and a melting point of 272 °C. Dipotassium ethylenediaminetetraacetate has a wide range of uses. It can be used to complex metal ions and separate metals. It is also used in detergents, liquid soaps, shampoos, agricultural chemical sprays, antidotes, and is commonly used in blood anticoagulants.     Dipotassium ethylenediaminetetraacetate (EDTA-2K) Dipotassium ethylenediaminetetraacetate can be used for complete blood counts. Whole blood cell analysis is widely used in clinical testing. Platelet count has become an important basis for the diagnosis and treatment of clinical thrombosis and bleeding diseases, and it is also one of the important parameters for preoperative detection of surgical patients. The International Committee for Blood Standards recommends the use of dipotassium ethylenediaminetetraacetate (EDTA-K2) anticoagulant blood for complete blood counts.   Studies have also explored the detection of total bilirubin (TBIL), direct bilirubin (DBIL), total protein (TP), albumin (ALB), and alanine in anticoagulated plasma and serum of dipotassium ethylenediaminetetraacetate. Differences in the results of 8 liver function indexes including aminotransferase (ALT), aspartate aminotransferase (AST), γ-glutamyltransferase (GGT), alkaline phosphatase (ALP) and so on. Methods The above eight biochemical tests were performed on EDTA-K2 anticoagulated plasma and serum on an automatic biochemical analyzer, and the results were compared and evaluated.   The results showed that EDTA-K2 anticoagulated plasma compared with serum, the results of TBIL, TP, ALB, ALT, AST were not statistically significant, EDTA-K2 anticoagulated plasma ALP was significantly lower than that of serum, the difference was statistically significant, and GGT was slightly lower In serum, the difference was statistically significant, and DBIL was significantly higher than that in serum, and the difference was statistically significant. Therefore, EDTA-K2 anticoagulated plasma can be used for the detection of TBIL, TP, ALB, ALT, and AST. It is not suitable for the detection of DBIL and ALP. For the GGT test results, the reference range of EDTA-K2 plasma should be formulated or multiplied by the correction factor.   Application of dipotassium ethylenediaminetetraacetate (EDTA-2K): 1. Additives for vacuum blood collection tubes: The additive of vacuum blood collection tubes is an aqueous solution of dipotassium ethylenediaminetetraacetate (EDTA-2K), and 4mg of dipotassium ethylenediaminetetraacetate (EDTA-2K) is required for anticoagulation of 2ml of blood. Because the concentration is small, in order not to dilute the blood, 20μl of an aqueous solution containing 200g/L of ethylenediaminetetraacetate (EDTA-2K) 200g/L is generally pre-installed in each blood collection tube. The validity period of the blood collection tube is two years. When the operating environment changes slightly, such as temperature changes, water can easily evaporate to the pipe wall (especially the water in the plastic PET pipe solvent can penetrate the pipe wall and leak out), causing the EDTA-2K in the pipe to crystallize and crystallize quickly When collecting blood, the latter dipotassium ethylenediaminetetraacetic acid blood collection tube is required to be turned upside down at least 8 times in order to fully dissolve and mix the crystallized EDTA-2K in the blood. If the action is too large, the red blood cells will be destroyed and hemolyzed. Gathered and adhered and broken.   2. Prepare toilet deodorant. In parts by mass, it includes the following substances: 5-10 parts of acid salt, appropriate amount of ammonia, 50-70 parts of alcohol, 5-10 parts of urotropine, appropriate amount of dipotassium edetate, appropriate amount of isobutanolamine, water 60 to 80 copies. The deodorant can not only deodorize but also prevent scale, and the method of use is simple, the dosage is small, and the duration is long, and it has no corrosive effect on the toilet. The production method is simple, the raw material cost is low, and it is non-toxic, harmless and non-polluting.   3. Used as a complexing agent in liquid phase analysis. If the invention provides a tetrabutylammonium hydrogen sulfate buffer salt system for liquid chromatography detection, the solvent is water, and the solute includes tetrabutylammonium hydrogen sulfate and a buffer ion pair. The buffer ion pair is composed of potassium dihydrogen phosphate and phosphoric acid The solute also includes a complexing agent, and the complexing agent is preferably dipotassium ethylenediaminetetraacetate.   The tetrabutylammonium hydrogen sulfate buffer salt system provided above is stable within 24 hours without turbidity. Taking the analysis of related substances of moxifloxacin hydrochloride as an example, it can be seen that the tetrabutylammonium hydrogen sulfate buffer salt system stored at room temperature for 24 hours The chromatographic behavior of moxifloxacin, N-methyl impurity, impurity A, impurity B, impurity C, impurity D, and impurity E on the reversed-phase chromatography column is basically the same as that of the newly configured tetrabutylammonium hydrogen sulfate buffer salt system.   4. Prepare metal polishing agent. The polishing agent is based on dipotassium ethylenediaminetetraacetate (EDTA-2K), trisodium phosphate, dibutyl phthalate, sodium silicate, inorganic acid, dicarboxylic acid compound, tetrapolyricinoleate, biological Buffer, stabilizer, water-soluble surfactant, water as raw materials, and through a scientific content ratio, the polishing agent prepared from this can effectively remove impurities on the metal surface. It is not only convenient to operate, but also has a good polishing effect. Improve the production efficiency, and ensure the cleanliness and gloss of the metal surface, and improve the quality of the metal.   Desheng has been committed to the research and development of blood collection tube additives. It has 15 years of production experience and can provide customers with lithium heparin, sodium heparin, dipotassium EDTA and tripotassium EDTA. If you need it, please call for details.

헤페스의 전체 이름은 4가지 하이드록시에틸피페라진 에탄술포닉 산이고 CAS는 7365-45-9입니다, 헤페스가 종종 생물학적 버퍼, pH 버퍼 범위에서 사용됩니다 : 6.8-8.2, 헤패스 완충 용액의 주성분은 하이드록시에틸피페라진 에틸 황산입니다, 헤페스가 물에 녹은 양성적 버퍼입니다 그리고 금속 이온과 안정적 복소수를 형성하지 마세요. 그것은 7.2-7.4의 수소 이온 농도 지수에서 좋은 완충능을 가집니다. 그것은 대부분 생화학적 진단상의 키트, DNA / RNA 추출 키트와 PCR 진단상의 키트에서 사용됩니다.   다양한 생화학 반응에서 사용됩니다 : 1. 헤패스 완충 용액은 종종 여러가지 유형의 유기체, 세포-세포 부착, 단기간 세포 집합과 문화의 세포 배양 매체에서 버퍼 반응제와 세정 티슈와 세포를 위한 버퍼로서 사용됩니다 ; 2. 단백질 리서치에서, 파이프는 종종 양이온 교환 크로마토그래피에서 결합된 버퍼의 성분과 용리제로서 사용됩니다 ; 3. DNA 연구에서, 파이프는 인산 칼슘과 DNA 침전 형성 시스템을 위한 버퍼로서, 그리고 AFM과 일렉트로포레이션 실험을 위한 버퍼로서 사용됩니다. 4. 게다가 헤페스는 DNA와 제한 엔자임 사이의 반응에 어떤 간섭을 가지고 있고 단백질 함량을 결정하는 것은 라우리의 방법에 적합하지 않습니다. 5. 헤패스 완충 용액은 종종 생화학적 진단상의 키트, DNA / RNA 추출 키트와 PCR 진단상의 키트와 더불어, 오르가넬러의 조사와 대단히 변하기 쉬운, ph 민감성 단백질과 효소에서 사용됩니다. 6. RNA 핵구성 요소를 분리하고 분석하기 위한 반응 버퍼와 프리 하이브리다이제이션 버퍼와 이종 교배 버퍼 ; RNA와 T4RNA에 대해 사용됩니다. 분자 생물학 등급은 T4 RNA 리가제, 분리로 RNA의 3 '-마지막을 라벨링하고 핵 RNA의 반응 버퍼, 프리 하이브리다이제이션 버퍼와 이종 교배 버퍼의 부품을 분석하는데 사용됩니다.   헤페스 관련 사항 1. 대부분의 세포에 요구된 pH 7.2-7.4 이지만, 그러나 셀 문화를 위한 적절한 pH 배양되는 세포의 종류에 따라 변화합니다. 섬유아세포가 더 높은 pH (7.4-7.7)를 선호하는 반면에, 형질 전환 세포주의 도입은 신맛을 요구합니다. pH (7.0-7.4). 대부분의 배양액 이후로 (NaHCO3)와 이산화탄소가 나트륨 중탄산염의 체제에 의해 버퍼링되, 기상에 이산화탄소 농도는 배양액에 나트륨 바이카보네이트 농도 있어야 합니다. 기상에 또는 인큐베이터 공기에서 이산화탄소 농도가 5%에 설정된다고 NaHCO3의 양은 덧붙였으면 문화에 해법은 1.97g/L입니다 ; 이산화탄소 농도가 10%로 유지된다고 NaHCO3의 양은 덧붙였으면 문화에 해법은 3.95g/L입니다. 셀 문화 병마개는 가스 교환을 보증하기 위해 또한 팽팽하게 비틀어지지 말아야 합니다 ;   2. HCO3과 이산화탄소 버퍼 쌍을 사용하는 배양 용액의 pH 값은 불안정하고, 일정한 기간 동안 저장 뒤에 알칼리성인 경향이 있습니다. 만약 배양액의 pH 또한 빨리 변하면, 헤패스 완충 용액이 10-25mM의 최종 농도에 배양액에 추가될 수 있습니다 ;   3. 헤페스는 양성적 버퍼이고 대부분 산화성 인산화 반응, 무균 환경에서 단백질 합성, 광합성적 인산화, 이산화탄소 정착, 기타 등등과 같은 생물학적 조사에 사용했습니다 ; 헤페스는 금속 이오나스의 기판에 어떤 영향도 미치지 않고, 전자 현미경 검사 (TEM)에 전송에 적합합니다 ; 셀 문화 매체에, 장점은 그것이 노지지배 또는 세포 관찰 동안 상대적으로 끊임없이 계속되는 pH 값을 유지할 수 있다는 것입니다. 헤페스 (25mM)는 고농도 이산화탄소 배양 환경의 제한을 완화하기 위해 비카보네이트 버퍼을 대체로서, 또는 비카보네이트 버퍼 (10-15mM)의 추가로서 사용될 수 있습니다. 유용성 이산화탄소와 중탄산염은 또한 매우 좋은 세포 성장에 중요합니다.

The impact of the epidemic will cause some things to fall and inevitably some things will rise, such as Carbomer. As a cross-linked acrylic polymer, carbomer has good thickening performance and strong suspending ability. In addition to being used in hand sanitizers, it is also widely used in skin care lotions, creams, transparent gels, and hair styling. Gel can even be applied to batteries.   The main functions of Carbomer: 1. Thickening-can produce a wide range of viscosity and fluidity 2. Suspension—make insoluble components permanently suspended in the system 3. Emulsification—plays emulsification and stabilization in the oil/water phase Carbomer thickening mechanism: a. Salt thickening, the most common method is to change the acidic resin into an appropriate salt, so that the curled resin molecules are opened to cause thickening. In water and other polar solvents, use NaOH, KOH, NH40H Such neutralization can easily generate salt; in acute weak or non-acute solvents, organic amines should be used for neutralization. When the resin is used as an emulsifier, in order to achieve the best stability of the oil/water emulsifier, it is necessary to double neutralize the resin with a water-soluble inorganic base and an oil-soluble organic amine, so that the product is soluble in water and oil. Salt acts as a bridge between the oil phase and the water phase.   b. Light bond thickening, adding a hydroxyl donor to the resin, the resin molecule as a carboxyl donor can combine with one or more hydroxyl groups to form a hydrogen bond to thicken. This method takes time, which may range from 5 minutes to several Hours, the consistency can reach the highest value. The PH value of this kind of material is slightly acidic, and the dispersion can be heated to 70°C (but should not exceed) to speed up the thickening. Commonly used polyhydroxy and polyethoxy reaction agents: non-ionic surfactants, solvents, polyols, glycol-silane copolymers, polyethylene oxide, fully hydrolyzed polyvinyl alcohol, etc.     use: Carbomer has excellent thickening, gelling, adhesive, emulsifying, suspending and film-forming properties. As a thickener and emulsifier, it has the following applications in the pharmaceutical industry:   1. Controlled-release drugs made as slow-release materials, such as ascorbic acid, aspirin, lithium carbonate, atropine sulfate, procaine hydrochloride, chlorpheniramine, quinine sulfate, theophylline and so on.   2. The application in the formulation of external medicines, as a carrier matrix to make ointments, suppositories, creams, gels, emulsions, etc.   3. Utilizing the gel, adhesive and film-forming properties of this product, the application in bio-adhesive, as a carrier matrix and bio-attachment made of drugs, it stays in the tissue mucosa for a long time and improves the bio-adhesion of the drug. Utilization, such as targeting mucous membranes, including ocular, nasal, intestinal, vaginal and rectal mucosa.   4. Utilizing the suspending ability of this product, it can effectively suspend insoluble components to form a uniform dispersion system, which is used in oral suspensions, which is safe and effective, avoids odor, maintains stability, and improves bioavailability.   In order to increase production capacity, Desheng actively applies new equipment and expands production staff. While ensuring production capacity, it must also pay attention to product quality. Carbomer series products that are in high demand are Carbomer 940 and Carbomer 980. Desun can provide high-quality Carbomer series raw materials.

Tris base is named tris(hydroxymethyl)aminomethane; tromethamine; tromethamine; 2-amino-2-(hydroxymethyl)-1,3-propanediol. It is a white crystal or powder. Soluble in ethanol and water, slightly soluble in ethyl acetate and benzene, insoluble in ether and carbon tetrachloride, corrosive to copper and aluminum, and irritating chemicals.   Tris is a weak base, and its pKa is 8.1 at 25°C; according to the buffer theory, the effective buffer range of Tris buffer is between pH 7.0 and 9.2. The pH of the aqueous solution of Tris base is about 10.5. Generally, hydrochloric acid is added to adjust the pH to the desired value to obtain a buffer of the pH value. But at the same time, attention should be paid to the influence of temperature on the pKa of Tris.   Tris is often used as a biological buffer, and is often formulated with pH values ​​of 6.8, 7.4, 8.0, and 8.8. Its pH value varies greatly with temperature. Generally speaking, for every degree of temperature increase, the PH value drops by 0.03. tris structure 1M Tris-HCl 6.8 and 1.5M Tris-HCl 8.8 are the most commonly used reagents for SDS-PAGE. And TAE, TBE, etc. prepared by Tris are the most commonly used reagents for DNA electrophoresis, and TE (pH 8.0) is mainly used to dissolve DNA. (TE is the collective name of Tris and EDTA.)   Tris buffer is not only widely used as a solvent for nucleic acids and proteins, but also has many important uses. Tris is used for protein crystal growth under different pH conditions. The low ionic strength of Tris buffer can be used for the formation of the intermediate fiber of C. elegans nuclear lamin (lamin). Tris is also one of the main components of protein running buffer. In addition, Tris is also an intermediate for the preparation of surfactants, vulcanization accelerators and some drugs. Tris is also used as a titration standard.   The Tris buffer developed and produced by Desheng is used for the preparation of buffers in biochemistry and molecular biology experiments; the preparation of pharmaceutical intermediates and the preparation of kits.

Due to a sudden new coronary pneumonia in early 2020, Virus Transport Media appeared in the public eye. But what exactly does it do, I think most people still don't know. Let's first talk about the role of inactivated Virus Transport Media. What is inactivation? Inactivation refers to the use of physical or chemical means to kill viruses, bacteria, etc., but does not damage the useful antigens in their bodies.   Inactivated virus: The high-level structure of the virus protein is destroyed, and the protein no longer has physiological activity, so it loses the ability to infect, cause disease and reproduce, but the conventional inactivation does not affect the primary structure of the virus protein, which means the sequence of the virus protein no change.     Inactivated Virus Transport Media: It is a colorless and transparent liquid, suitable for various types of viruses, new coronaviruses, various influenza, avian flu, hand, foot and mouth urticaria and other viruses. A high concentration of guanidine salt is used to achieve rapid inactivation and preservation of respiratory pathogens, so that the sample loses infectivity. The inactivated samples can be used with the corresponding new coronavirus RNA extraction kit, M32/M96 nucleic acid extractor, etc. to quickly extract viral nucleic acid, and the new coronavirus PCR detection kit can be used to achieve rapid detection without specific sensitivity. influences. Applicable kit methods: fluorescent PCR method, combined probe anchoring polymerization sequencing method, constant temperature amplification chip method, magnetic particle chemiluminescence method, colloidal gold method.   It has the following advantages: 1. Efficiently inactivate viruses to avoid cross-infection caused by centralized sampling 2. Inactivate the virus, reduce the difficulty of storage and transportation 3. The sample loses its infectivity and protects the testing personnel 4. Widely used in PCR laboratory   The product developed and produced by Desheng is suitable for the collection, preservation and transportation of common virus samples such as new coronavirus, influenza virus, hand, foot and mouth virus. Pharyngeal swabs, nasal swabs or tissue samples of specific parts can be collected, and the stored samples can be used for subsequent clinical experiments such as nucleic acid extraction or purification.

Hand-washing sanitizing gel is a daily chemical product that is often used in daily life. Because of the new crown epidemic, it has made it widely welcomed by the public. Carbomer 980, a very important raw material in the sanitizing gel, has also become more and more biochemical. Favored by reagent manufacturers.   Carbomer is used in hand sanitizing gel. The main reason is its thickening, viscosity and permeability. Compared with hand sanitizer, most people prefer gel products. Carbomer can be used to change the solution. It is gel-like, which is more durable and easier to use than liquids. The concentration of carbomer is basically in the range of 0.2%-0.5%. Carbomer can make the liquid system have a special yield value and rheology. Only a very low concentration can make some insoluble additives (particles, oil droplets) Etc.) Achieve permanent suspension.     It is precisely because of the strong levitation ability of carbomer that carbomer is widely used. In addition, carbomer can achieve a good transparency effect when used in hand washing and disinfection gel. After being neutralized and ionized by the carboxyl group, due to the mutual repulsion of negative charges, the molecular chain is dispersed and stretched, showing a greatly expanded state. It is sticky, and these characteristics undoubtedly make Carbomer one of the important raw materials for hand-washing disinfection.   The most notable feature of the use of hand-washing disinfection gel is that it avoids repeated washing, does not need to be washed with water, and can effectively inhibit and remove bacteria from the hands. Especially in summer, the growth rate of bacteria increases, especially intestinal pathogens, pyogenic cocci, yeasts and other pathogens. The main bactericidal component of the hand-washing disinfection gel is ethanol. If it has antibacterial effect, there will be other antibacterial agents, and some use guanidine substances to inhibit bacteria. The content of antibacterial agents is generally a few tenths of a percent, up to 23%, and the national standard also has clear requirements for the content of various antibacterial agents.   With the spread of the new crown epidemic at home and abroad, the supply of disinfection products is in short supply in a short period of time. Especially the disposable hand sanitizer used to sterilize hands when going out has been snatched wildly. Carbomer 980 is used as the free hand sanitizer. As one of the ingredients, many manufacturers have raised their prices. Some manufacturers cannot supply normally because of too many orders. However, as one of the newly developed manufacturers of carbomer products, Desheng can not only guarantee the normal supply of products, but also maintain the prices. Does not rise, is a true conscientious producer.

Carbomer is a copolymer of polyalkyl sucrose or polyalkyl pentaerythritol and acrylic acid cross-linked polymer. It can form a high-viscosity gel at a very low concentration (usually 0.2-1.0%) and is widely used Daily chemical, pharmaceutical and other industries. But it has a lot of models, even with similar names, can these different models be replaced with each other?   The first thing you need to understand is the meaning of different models of carbomer, mainly based on the different materials used in polymerization and the degree of polymerization, so there are a variety of different specifications and models of carbomer. Commonly used in the market are carbomer 980, carbomer 940, carbomer U20, etc., and their thickening performance, emulsification performance, viscosity, shear resistance, etc. are different, so most cases cannot be replaced by each other of. Some characteristics of different carbomers are listed below:     Carbomer Clear Gel Carbomer 940: It is characterized by good thickening performance, extremely short rheology, high viscosity, medium clarity, low ion resistance and high shear resistance, suitable for creams, lotions and gels.   Carbomer 941: It is characterized by stable emulsification system, low viscosity, long rheology, high-definition clarity, medium ion resistance and low shear resistance. Even in ionic solutions, stable emulsions or high Transparent gel.   Carbomer 980: The viscosity is higher than 940, the ion resistance is better than 940, the transparency is equivalent, and it is nourishing than 940 when used in skin care products.   Carbomer U20: excellent dispersibility, high thickening performance, long rheology, good transparency, good suspending ability, stable emulsification system, and no stickiness. It can be used in creams or lotions instead of traditional carbomer 934 , Instead of Carbomer 940 or 980 for transparent gel.   Judging from the characteristics of the respective models, different carbomers are not completely irreplaceable, but generally speaking, the carbomer model used in a product is fixed, but for newly developed products, it is still necessary to test multiple models of carbomer. Therefore, it chooses the best performance, and with the update of technology, the development of better performance carbomers will come out, which will replace some traditional carbomers. Desheng Technology has many years of R&D and production experience in Carbomer and other acrylate polymer materials manufacturers, and welcomes users to communicate!

Carbomer, also known as carbomer, is a polymer formed by chemical cross-linking of acrylic acid or acrylate and allyl ether, including polyacrylic acid (homopolymer) and long-chain alkanol acrylates Polymer (copolymer). Its molecular structure contains 52-68% acid groups, so it has a certain acidity, has hydrophilic properties, and can be dissolved in water, ethanol and glycerin. Carbomer has the functions of thickening, suspending, stabilizing the system, regulating the release of water and active substances, and has simple process and good stability. Therefore, it is a rheological modification widely used in personal care products, pharmaceuticals and other fields. Thickener. There are two main thickening mechanisms of carbomer, including neutralization thickening and hydrogen bond thickening. 1. Neutralization and thickening Because it contains a certain acid group, it needs to be alkaline neutralized during the application process. After being neutralized by alkali, the carboxyl group of the carbomer is ionized. Due to the mutual repulsion of negative charges, the curled molecular chain stretches into a greatly expanded state, which increases the original volume to about 1000 times. To the effect of thickening. Commonly used neutralizers are sodium hydroxide, potassium hydroxide, potassium bicarbonate, and triethanolamine (the pH is adjusted to about 7 to get a crystal clear gel), which is why carbomer is sensitive to ions. 2. Hydrogen bond thickening Carbomer molecules, as carboxyl donors, can combine with one or more hydroxyl groups to form hydrogen bonds and thicken. This reaction mechanism takes time. Commonly used hydroxyl donors are non-ionic surfactants, polyols and so on. In addition, the following points need to be paid attention to when using carbomer. Precautions: 1. All carbomer polymers have the ability of shear thinning, and the longer the shear time, the slower the viscosity recovery, and even the permanent loss of viscosity; 2. Carbopol polymer has poor tolerance to ions, and Carbopol 1342, which is in the transitional stage, is relatively high; 3. Ultraviolet radiation will cause loss of the viscosity of carbomer, and this loss is irreversible.

With the increasing demand for nucleic acid testing projects, Virus Transport Media’s procurement needs are also getting higher and higher. The ingredients of Virus Transport Media are: Hanks Liquid Foundation, Gentamicin, Fungal Antibiotics, BSA (V), Cryoprotectants , Biological buffers and amino acids, etc.   Virus Transport Media is suitable for the collection, preservation and transportation of common virus samples such as new coronavirus, influenza virus, hand, foot and mouth virus. Pharyngeal swabs, nasal swabs or tissue samples of specific parts can be collected, and the stored samples can be used for subsequent clinical experiments such as nucleic acid extraction or purification.     The collection method of Virus Transport Media: 1. Pharyngeal swab: Use two plastic rod swabs with polypropylene fiber heads to wipe both pharyngeal tonsils and back wall at the same time, immerse the swab heads in 3ml Virus Transport Media (also can use isotonic saline solution, tissue culture Discard the tail part of the tube with liquid or phosphate buffer solution), and screw the tube cap tightly.   2. Nasal swab: Gently insert a plastic rod swab with a polypropylene fiber head into the nasal palate in the nasal passage, stay for a while and then slowly turn it out. Take another plastic rod swab with polypropylene fiber head and collect the other nostril in the same way. The above two swabs were immersed in the same tube containing 30% of the sample liquid, the tail was discarded, and the tube cap was screwed tightly.   3. Nasopharyngeal aspiration or respiratory tract aspiration: Use a collector connected to a negative pressure pump to extract mucus from the nasopharynx or extract respiratory secretions from the trachea. Insert the head of the collector into the nasal cavity or trachea, turn on the negative pressure, rotate the head of the collector and slowly withdraw, collect the extracted mucus, and rinse the collector once with 3ml sampling solution (you can also use a pediatric catheter connected to a 50ml syringe Come up to replace the collector).   The cell preservation solution is a general-purpose cell cryopreservation solution, which can be used to freeze human and various animal cell lines; the complete cryopreservation solution formula is ready to use, convenient and fast; non-program cooling, -80℃ low temperature refrigerator freezing Store up to 5 years to ensure the safety of cryopreserved cells; cryopreservable plates (cell culture plates) can be used for cryopreservation of hybridoma cells. The cell preservation solution has a diluting effect and can be separated and embedded in mucus. The effective cells can be preserved, and provide sufficient cell numbers to ensure the accuracy of the test results. At the same time, the processed sample can be completely removed after the low-speed centrifugal filtration of the mucus in the sample, which is effective Prevent mucus from interfering with the sample test results. The cell preservation solution can be made into a uniform monolayer cell sheet after low-speed centrifugation, which meets the inspection requirements.   Apart from professionals, many people often confuse the cell preservation solution with Virus Transport Media, thinking that the two refer to the same preservation solution. In fact, the cell preservation solution is mainly used to freeze cells, and Virus Transport Media has There are two types of fire-extinguishing and non-extinguishing types. The fire-extinguishing type is mainly used for nucleic acid detection. For example, the more popular new coronavirus nucleic acid detection is the fire-extinguishing Virus Transport Media. The non-extinguishing type is mainly used for virus cultivation and reproduction. The biggest feature is that it can provide more accurate test results.